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diagnosis nephrology differential hypokalemia causes hyponatremia pathophysiology alkalosis antiarrhythmics cardiology chloride classification evaluation hypotonic management metabolic perioperative pharmacology phases physiologic
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... Bartter syndrome, Gitelman ... Differential #Diagnosis #Algorithm ... #causes #potassium
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... treated with IV potassium ... consumption • Low ... Bartter syndrome, Gitelman ... #nephrology #low
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Differential Diagnosis Algorithm ... Bartter's syndrome, Gitelman's ... Differential #Diagnosis #Algorithm ... #nephrology #causes ... #low #potassium
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... wasting) • Hypomagnesemia ... Supplement: • Potassium
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... alkalosis • Normal/low ... Bartter syndrome, Gitelman ... the indicated causes ... and potassium acid
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Cerebral salt wasting ... Hypothyroidism, Low ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
moving back to resting ... Phase 4 - True Resting ... maintain a negative resting ... 1 - Sodium Channel ... 3 - Potassium Channel
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... : SIADH, Renal Sodium ... can be high or low ... Cerebral Salt Wasting ... Uosm <100): Renal Losses
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Performance thorough ... ASA class If ... event, follow ACC algorithm ... Orthopedic • Low ... surgery Stress Testing
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl > 1.6, low ... confirmed via genetic testing ... correcting serum potassium ... continued in most cases
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