1118 results
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach to Acute ... tubular proteinuria, granular ... MatthewHoMD #Acute
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
concentrated urine Granular ... Muddy-brown" heme-granular ... casts are seen in acute
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... overt cytoplasmic granules ... #Auer #Rods #Acute
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... are typical for acute
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... in a variety of acute ... ) • Granular Casts
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
tubular cells - Acute ... renal disease • Granular ... protein indicating acute
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... diagnosed with acute ... decreased secondary granules ... also described in acute
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
histamine in their granules ... translocation • Acute ... thrombocythemia • Acute
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL (Acute Lymphoblastic ... Lymphadenopathy AML (Acute ... Blasts APML (Acute ... distinctive primary granules
Examples of varying granular and granular/waxy mixed casts: 
A: coarse granular/broad-waxy (and surrounding white blood cells);
Examples of varying granular ... and granular/waxy ... casts: A: coarse granular ... /muddy brown granular ... #Granular #MuddyBrown