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Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... promyelocytic #leukemia
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
T-LGL leukemia - ... T-CeIl Large Granular ... Lymphocytic Leukemia ... Predominantly leukemic ... #Lymphocytic #Leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... Lymphoblastic Leukemia ... distinctive primary granules
Chronic Myelomonocytic Leukemia (CMML) • Definition • DDx • Dx Tool and Risk Stratification • Treatment
Myelomonocytic Leukemia ... • Treatment Algorithm ... Myelomonocytic #Leukemia
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... tubular proteinuria, granular ... Nephritis #AIN #Algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Differential Diagnosis Algorithm ... Neoplastic: - Leukemia ... Lymphoblastic Leukemia ... Chronic Lymphocytic Leukemia ... Differential #Diagnosis #Algorithm
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... promyelocytic leukemia ... decreased secondary granules ... acute myeloid leukemia ... mixed lineage leukemia
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 Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... acute myelogenous leukemia
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
histamine in their granules ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Acute basophilic leukemia
Chronic Neutrophilic Leukemia (CNL) • Signaling Pathway • WHO Dx Critera • Risk Stratification • Treatment
Chronic Neutrophilic Leukemia ... • Treatment Algorithm ... #Neutrophilic #Leukemia
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