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diagnosis differential management clinical algorithm causes pathophysiology treatment nephrology criticalcare endocrinology pharmacology pocus workup table comparison radiology signs symptoms cardiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipid • GH excess ... metabolic abn #GrowthHormone ... #GH #FeedbackLoop
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... of onset of GH excess ... GH excess prior ... GH excess after ... fraction • HTN #GrowthHormone
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Prolactin #PRL #FeedbackLoop
Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
Hyperplasia Androgen Excess ... DHEAS Estrogen Excess ... Glucocorticoid Excess ... ) Aldosterone Excess
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Hypernatremia - Excess ... consciousness • No access
The components of the adrenal gland and consequences of excess hormone production #Pathophys #MedStudent #Conn #Cushing
consequences of excess
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Biopsy Androgen Excess ... Hyperplasia) Estrogen Excess ... Glucocorticoid Excess ... ) Aldosterone Excess
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table Diabetes Insipidus - Inadequate ADH SIADH -
Inadequate ADH SIADH - Excess
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
Glucocorticoid excess ... Catecholamine excess ... Mineralocorticoid excess
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