11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
ACLF) Clinical Guidelines ... underlying liver disease ... Liver Injury (DILI ... #Cirrhosis #Hepatology ... #gastroenterology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... symptoms of liver disease ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
) - Stepwise Diagnosis ... Algorithm DILI ... Alcohol-related liver disease ... dechallenge • Acute ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... #differential #diagnosis ... #algorithm #hepatology
Causes of Encephalopathy - Differential Diagnosis Algorithm
Hyperacute:
 - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
- Differential Diagnosis ... Algorithm Hyperacute ... encephalopathy Acute ... conditions: Heart failure ... neurocognitive disease
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential Diagnosis ... Algorithm Portal ... • Infiltrative disease ... • Acute liver ... #Algorithm #Hepatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
- Follow local guidelines ... splenomegaly, abnormal neurology ... , back pain Haematology ... #Limping #NWB #Algorithm ... Peds #Pediatrics #Diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... of cholestatic disease ... Alcoholic liver disease ... liver #chemistry #diagnosis ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Treatment: - Acute ... - Concomitant diseases ... HCV, DILI, HCC, ... - Multiorgan failure ... #hepatology
Pulmonary Histoplasmosis
Quick Facts on Histoplasma capsulatum:
 • Dimorphic fungi, in yeast phase within the body
 •
droppings Making the Diagnosis ... Antigen testing, Serology ... Duration depends on acute ... for respiratory failure ... (guidelines / data