37 results
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hemophagocytic Lymphohistiocytosis ... (HLH) Clinical Features ... EricsMedicalLectures/ #HLH #Hemophagocytic ... Lymphohistiocytosis #diagnosis #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... Common Clinical Features ... vasculitis • Hematologic ... criteria for 1) hematologic ... arteritis (4%) Genetic Features
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome ... Distinguishing Features ... Stevens #Johnsons #Syndrome ... Comparison #Diagnosis #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... A subset of hemophagocytic ... Histopathologic features ... Diagnosis #Management #Hematology ... #Rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) - Diagnosis
Clinical Features:
 • Altered mental status (Either lethargy, confusion, or
Encephalopathy Syndrome ... Diagnosis Clinical Features ... Factor + Clinical Features ... Encephalopathy #Syndrome ... #Diagnosis #Neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Features Required ... or hyporeflexia Features ... Elevated CSF protein Features ... spectrum disorders Features ... diagnosis #criteria #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... (+) Systemic Features ... (-) Systemic Features ... capillary leak syndrome ... Differential #Diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... annually in US Features ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Typical clinical features ... necrosis HELLP Syndrome ... Typical clinical features ... Typical clinical features ... Disease #Pregnancy #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Overwhelming clinical syndrome ... • Supportive measures ... TheIDtrivia #HLH #Hemophagocytic ... management #treatment #hematology