93 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment Algorithm ... for MAS / HLH ... #MAS #HLH #Hemophagocytic ... Management #Treatment #Algorithm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... (HLH) Pathophysiology ... Chediak-Higashi, Griscelli, Purtilo ... Drugs, Unknown cause ... #Hemophagocytic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... A subset of hemophagocytic ... lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Plasma exchange #MAS
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... steroids • In mild cases ... underlying condition may ... Options for severe cases ... #Hemophagocytic
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... and Screen for HLH ... HLH syndrome 5. ... • Hypoplastic MDS ... Differential #Diagnosis #Algorithm
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... and Screen for HLH ... HLH syndrome 5 ... • Hypoplastic MDS ... Differential #Diagnosis #Algorithm
Causes of Female and Male Infertility - Differential Diagnosis Algorithm
Causes of Female Infertility:
 • Uterus -
Causes of Female ... Differential Diagnosis Algorithm ... hypogonadism) Low FSH/LH ... problem) High FSH/LH ... Differential #Diagnosis #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Alloimmune • anti-HLA ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
Amyloidosis • HLH ... Differential #Diagnosis #Causes ... #Algorithm #Oncology
Important Respiratory Distress Pearls

#diagnosis #respiratory #distress #NRDS #RDS #TTN #MAS #neonatal #pediatric #adult #respiratory #adverse #effects
NRDS #RDS #TTN #MAS ... #ventilation #algorithm ... #causes