75 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment Algorithm ... for MAS / HLH ... #MAS #HLH #Hemophagocytic ... Management #Treatment #Algorithm
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... Auto-amplification loop Diagnosis ... Chediak-Higashi, Griscelli, Purtilo ... Drugs, Unknown cause ... #Hemophagocytic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Activation Syndrome (MAS ... A subset of hemophagocytic ... lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Activation #Syndrome #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... steroids • In mild cases ... underlying condition may ... Options for severe cases ... #Hemophagocytic
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... and Screen for HLH ... HLH syndrome 5. ... • Hypoplastic MDS
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... Algorithm Consumption ... and Screen for HLH ... HLH syndrome 5 ... • Hypoplastic MDS
Causes of Female and Male Infertility - Differential Diagnosis Algorithm
Causes of Female Infertility:
 • Uterus -
- Differential Diagnosis ... Algorithm Causes ... problem) High FSH/LH ... #Differential #Diagnosis ... #Algorithm #Causes
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
Differential Diagnosis ... Amyloidosis • HLH ... #Differential #Diagnosis ... #Causes #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Algorithm Decreased ... Alloimmune • anti-HLA ... #Algorithm #Causes
Important Respiratory Distress Pearls

#diagnosis #respiratory #distress #NRDS #RDS #TTN #MAS #neonatal #pediatric #adult #respiratory #adverse #effects
Distress Pearls #diagnosis ... NRDS #RDS #TTN #MAS ... #ventilation #algorithm ... #causes