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diagnosis management algorithm differential treatment nephrology hepatology hematology causes clinical pharmacology endocrinology syndrome criteria pathophysiology ascites classification comparison oncology pocus
Risk factors for atherosclerosis Modifiable risk factors: - Dyslipidemia (elevated LDL, decreased HDL) - Tobacco smoking -
Dyslipidemia (elevated LDL ... , decreased HDL)
Fibrates - Gemfibrozil and Fenofibrate Mechanism: activates PPAR alpha Lipid Effects: - Decrease TG by 30-50% -
50% - Increase HDL ... - Decrease LDL
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Hypothyroidism Decreased HDL ... Androgens Increased LDL
#Estrogen 25-OH-D3 formation #HDL #LDL #VLDL Y Proliferation and desquamation of #vaginalepithelium In children: delayed epiphyseal fusion #Osteoporosis Atherosclerosis Vaginal infections Tall stature #Progestogen #mammarygland tubes No buildup of uterus
OH-D3 formation #HDL ... #LDL #VLDL Y
Diabetes 10 year risks for average male (female - within — 1-2% for almost all endpoints)
total chol 5, HDL
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
/Secretion → ↑ LDL ... Production → ↑ LDL ... Receptors → ↑ LDL ... Clearance → ↓ Plasma LDL-C
Hemoglobin A1c (glycated hemoglobin) reflects the average blood glucose concentration over the course of the RBC
calculate eAG (in mg/dL ... follows: eAG (mg/dL ... triglycerides, and LDL ... correlation with HDL
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
calcium > 11 mg/dL ... / >1 mg/dL the ... disease - Cr >2 mg/dL ... Hemoglobin < 10 g/dL ... or <2 g/dl LLN
ACC/AHA Statin Guidelines - 2013 vs 2017 In 2013 the ACC/AHA guidelines drastically changed the way we
the traditional LDL ... group, if the LDL ... alternatively use the LDL ... of the target LDL ... expect a >50% LDL
HAS-BLED Score - Hypertension: Baseline SBP > 160mmHg - Renal disease: Cr > 2.6mg/dL, on HD,
disease: Cr > 2.6mg/dL ... , on HD, or s/p
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