22 results
Kaposi Sarcoma Herpes Virus (KSHV)

By Dr. Sara Dong @swinndong via #IDFellowCase
#ID  #Infectious Diseases  #Infections
#Differential
IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV ... lymphoproliferative #KICS
KSHV Inflammatory Cytokine Syndrome (KICS)

By Dr. Sara Dong @swinndong  via #IDFellowCase
#ID  #Infectious Diseases
Cytokine Syndrome (KICS ... IDFellowCase #ID #Infectious ... Diseases #Infections ... Diagnosis #KSHV #HHV ... #KICS #Kaposi
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... 20%) congenital infection ... herpes virus 6 HHV ... herpes virus 7 HHV ... Herpes #Viruses #HHV
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Infection-Related ... Cancers Viruses: • HPV ... T-cell Leukemia • HIV ... carcinoma • HHV ... @drkeithsiau #Infection
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... gut) • Viruses: HSV ... airways) • Viruses: HSV ... reactivation), HHV ... #Transplant #Infections
Travel History - Clues to Infectious Disease Diagnosis in a Traveler 
 • Where did you
History - Clues to Infectious ... Schistosomiasis • Skin contact ... Herpesvirus B infection ... • Sexual contact ... InfectiousDiseases #Infections
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Acquired HLH: • Infections ... Virus (EBV, CMV, HHV8 ... Still disease, Infection ... Etiological+++: Anti-infectious
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Preventing and Treating HHV ... and uncontrolled HIV ... activity against HHV ... adjunctive therapy #HHV8 ... opportunistic #infections
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
Cytokine Syndrome (KICS ... Definition for KICS ... if present Infectious ... ID_fellows #KICS ... diagnosis #management #hhv8
Hansen's Disease (Leprosy)
 • Transmission - not completely understood, ?nasal droplets
 • Symptoms appear ~5 years
people do not contract ... factors: Close contact ... chemotherapy, SOT, HIV ... x 24 m BIDMC Infectious