26 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... Non-lmmune: • HELLP Syndrome ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... Risks factor for HIV ... plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - HCV - HIV ... immunodeficiency virus (HIV ... Treatment: ... result from low blood
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... necrosis) • VIT ... Ig A vasculitis/HSP
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Aseptic necrosis of hip ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia ( ... Leucopenia/lymphopenia, Thrombocytopenia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... deficiency) • HIT ... Treat primary cause ... #treatment #management ... #hematology
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
elevation • Nausea ... 14%), in which case ... enzymes ↑ • Mild anemia ... • Thrombocytopenia ... antibody test) Treatment
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemostasis: - Thrombocytopenia ... ITP - APLS - HIT ... : • Complete blood ... #dermatology #physicalexam
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Brucellosis - Viruses: HIV ... Knee #Effusions #causes ... differential #diagnosis #msk ... #physicalexam