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diagnosis differential neurology erythematosus hematology lupus sle vasculitis algorithm als amyotrophic arteritis autoantibodies autoimmune behcet chronic classification cll common cord
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... Other auto-immune, Infectious ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... Infections: - ... HIV, CMV, HTLV ... Inflammatory: ... , Sjogren syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: - Ocular inflammatory ... to exclude are infections ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (25-75%): Inflammatory ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... , particularly scleritis ... purpura: Strong sign ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... sx + signs/sx of ... complaints- anemia ... GCA #Temporal #Signs ... #Management
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