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diagnosis differential neurology erythematosus sle vasculitis algorithm als amyotrophic autoimmune behcet classification disorders hematology lateral mimickers monoclonal ms multiple myelitis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... #Diagnosis #autoantibodies ... #signs #symptoms ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... Infections: - ... HIV, CMV, HTLV ... Inflammatory: ... , Sjogren syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Zone Lymphoma (HCV ... • Heavy Chain disease ... macular Vasculitis) Autoantibodies ... (-) hemolytic anemia ... • Lupus anticoagulant
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... photosensitivity, inflammatory ... • Anti-Ro/SSA autoantibodies ... fibromyalgia) • Infections ... : • Symptoms limited
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: - Ocular inflammatory ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... Cryoglobulins • HIV
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... • Bilateral signs ... and/or symptoms ... simplex virus, HIV ... Myelitis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (25-75%): Inflammatory ... matter, spinal cord ... #signs #symptoms ... #rheumatology #
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the nervous system ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
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