12 results
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV-Associated Neurocognitive ... Definition: HIV-Associated ... • Depressive symptoms ... The clinical syndrome ... disorder #dementia #AIDS
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... • Recurrent infections ... acute leukemia • Associated ... Anemia #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... Differential Diagnosis: Infection ... • Steroids: IV ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... and symptoms can ... mimic common infections ... Lymphohistiocytosis #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... /AIDS patients ... be present: • AIDS ... Other Pathogens Associated ... Differential #Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
to exclude are infections ... Presentation - Systemic Symptoms ... purpura: strong sign ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease associated ... meningitis), MCC CNS symptoms ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Physical Exam/Signs ... • Richter’s Syndrome ... Transform to DLBCL, PML
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 syndromes ... • CT: Halo sign ... Constitutional symptoms ... #HIV #AIDS #pulmonary
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... VASCULITIS: ANCA Associated ... Differential #Diagnosis #Rheumatology