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causes ana antibody antinuclear disease management patterns acidosis agglutinin algorithm anemia apml arthritis autoimmune cancer cold criticalcare dermatology differentiation disorders
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... of breath • Neurologic ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... Risks factor for HIV ... /HCV testing - ... (CVID, WAS), (neurologic ... #Workup #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... body-like: - Neurologic ... Rods/rings: - HCV ... #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Cytoplasmic Patterns ... body-like: • Neurologic ... Rods/rings: • HCV ... #differential # ... diagnosis #rheumatology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Diagnosis and Screening ... Testing Common ... (correction of hypokalemia ... #Screening #Workup ... #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Infection - Viral (HIV ... symptoms: - Muscle pain ... - Abdominal pain
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Hypotension & Hypovolemia ... Demand: Stress / Pain ... Beta-Agonists, ↑ work ... separate D-lactate testing
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... lesions • Severe pain ... deficiency Work ... antineutrophil cytoplasmic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... • Steroids: IV ... #management #hematology ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Mycoplasma, EBV, HIV ... younger pts) Differential ... chills, flank pain ... hemolytic #anemia #hematology
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