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causes oncology anemia nephrology product reactions agglutinin apml cd4 classification cold differentiation disease disorders hematuria hemolytic hodgkins icl idiopathic kidney
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- CMV - HCV ... - HIV • Immune ... immunodeficiency virus (HIV ... Anemia #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... Risks factor for HIV ... , HCV - Alcohol ... smear, HIV/HCV ... #Workup #hematology
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
(HPV, EBV), Renal ... (Goodpasture's syndrome ... #diagnosis #kidney ... #blood #urine # ... management #treatment
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
chemotherapy) • Genetic syndromes ... Heme (lymphoma. aplasia ... myelodysplasia) • Infections ... - HIV. ... #hematology #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... , HIV, rubella legionella ... younger pts) Differential ... sensitize red blood ... hemolytic #anemia #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Diagnosis Neonate ... hypertension and/or drug treatment ... including white blood ... cell aplasia DOI ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Causes • Anemia • Aplastic ... • Parvovirus infection ... count with differential ... #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... initiation • Differential ... Diagnosis: Infection ... • Steroids: IV ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
due to marrow aplasia ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
and Management ... Statins - ETOH - Infection ... - Viral (HIV, Influenza ... UA positive for blood ... #Diagnosis #Management
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