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diagnosis management causes syndrome aids barre rhabdomyolysis cauda caudaequina cns dementia disorder encephalopathy equina gbs guillainbarre hand infections infectiousdiseases myelitis
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
• Infectious: HIV ... Inflammatory/AI: CIDP, Guillain-Barre ... Malignancy: Paraprotein-associated ... Peripheral #Neuropathy #differential ... diagnosis #causes #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Pathophysiology ... Campylobacter jejuni - HIV ... GQ1b IgG Antibody associated ... Treatment: • Plasmapheresis ... #neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV-Associated Neurocognitive ... Definition: HIV-Associated ... dementia Pathophysiology ... Treatment: • HAART ... dementia #AIDS #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in HIV ... Principles of HIV-Associated ... Infections in HIV ... encephalopathy #HIV ... InfectiousDiseases #Neurology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Heat iniury, Heat stroke ... Infection (Viral- HIV ... Dermatomyositis) AKI - Pathophysiology ... Heme associated
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Impairment: • Acute stroke ... parainfluenza, Coxsackie, HIV ... Neoplastic: Malignancy-associated ... aminotransferases • Serology ... #Diagnosis #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... the underlying pathophysiology ... and cauda equina TREATMENT ... diagnosis #management #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Heat injury, Heat stroke ... Infection - Viral (HIV ... Heme associated ... #nephrology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
constipation Differential ... cord infarct • HIV ... Tethered cord • Guillain-Barre ... axial T1 and T2 Treatment ... diagnosis #causes #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
fluctuations PRES-Associated ... Etiology: • Pathophysiology ... Reversible course Differential ... Constipation, Seizures, Stroke ... diagnosis #management #neurology
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