30 results
Proposed Treatment Algorithm for MAS / HLH

#MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hemophagocytic Lymphohistiocytosis ... (HLH) Clinical ... lab findings in HLH ... consistent with HLH ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... Primary HLH: - ... HLH-94 Protocol ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... (HLH) Definition ... / Diagnosis: HLH ... If no response HLH ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... (HLH) Pathophysiology ... • Familial HLH ... XLP) Acquired HLH ... #Hemophagocytic
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009

At least three of the following: 
 -
Hemophagocytic Lymphohistiocytosis ... (HLH) Diagnostic ... @PulmCrit #HLH ... #Hemophagocytic
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
acquired forms of haemophagocytic ... A subset of hemophagocytic ... lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH
Hypoplastic Left Heart Syndrome (HLHS)
 • Introduction
 • Embryology
 • Anatomy
 • Physiology of HLHS
 •
Heart Syndrome (HLHS ... Physiology of HLHS ... LeftHeart #Syndrome #HLHS
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
DKA vs HHS - Think ... of DKA and HHS ... emergencies - HHS ... like overlap DKA/HHS ... if HHS + poor PO
Algorithm for treatment of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar State (HHS)

#DKA #HHS #Algorithm #Diabetic #Ketoacidosis
Hyperosmolar State (HHS ... ) #DKA #HHS #