11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Pregnancy - TTP/HUS ... of Pregnancy (AFLP ... #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... @Bloodman #Thrombocytopenia ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... differential #diagnosis #algorithm ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
, HCV - Alcohol ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... or if a primary hematologic ... Causes #Workup #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... hepatitis serologies, HCV ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... #differential #Hepatology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... sepsis: chronic liver ... hemolytic anemia, CKD, hiv ... meds, chronic alcoholics ... #cellulitis #dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... DIC • Severe Liver ... causes #treatment #management ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... specifically immune thrombocytopenia ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... purpura & severe thrombocytopenia ... eruptions, diarrhea, liver ... Transfusion #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Petechial or purpuric rash ... leukopenia, anemia, and thrombocytopenia ... • Liver function ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology