16 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS ... presents with coagulation ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... EBV, CMV), Alcohol-related ... Injury #Diagnosis #Algorithm ... #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... ) • Advanced Liver ... Disease - Alcohol ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Kidney Failure Coagulation ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology ... gastroenterology #management
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... HAV immunity; Liver ... #Management #Treatment ... #Hepatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
hemorrhage, while under-coagulation ... #management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... differential #diagnosis #algorithm ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
- MAHA: TTP/HUS ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... • Albumin • Coagulation ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... #differential #Hepatology