24 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... normal - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... HAV immunity; Liver ... #Algorithm #Diagnosis ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... EBV, CMV), Alcohol-related ... e.g. ascites), Chronic ... Injury #Diagnosis #Algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • NAFLD • Alcohol ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... - ongoing ↑ LFTs ... gastroenterology #algorithm ... gastroenterology #hepatology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
antivirals (DAAs) for chronic ... DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... HepC #HepatitisC #Management
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... - NAFLD, Alcohol ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
D/E, EBV, CMV, HSV ... Drugs (MDMA), Alcohol ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... #differential #Hepatology ... transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #hepatology