19 results
Hepatitis B Phases and Treatment
Phase 1 - HBeAg+ Chronic Infection
Phase 2 - HBeAg+ Chronic Hepatitis
Phase 3
Hepatitis B Phases ... + Chronic Hepatitis ... - Chronic Hepatitis ... #HBV #HepBV #Phases ... #Treatment #Management
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... between the above phases ... HAV immunity; Liver ... Chronic Hepatitis ... #Treatment #Hepatology
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
antivirals (DAAs) for chronic ... DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... #Management #Pharmacology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... Injury (DILI) ... #Liver #Failure
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... normal - Hemolysis, NASH ... #Injury #hepatology ... #LFTs #transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... e.g. ascites), Chronic ... hepatitis fibrosis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... failure 1) Hepatocellular ... D/E, EBV, CMV, HSV ... Transaminitis #LFTs ... #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Failure (ALF): ... • Liver injury ... , Chronic viral ... : > 3 • Chronic
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... injury (INR > 2 ... failure #HepatitisB ... #Indications #management ... #hepatology
Phases of chronic HBV infection according to revised and classical definitions
Phase 1: HBeAg+ chronic infection (old
Phases of chronic ... HBV infection according ... #HBV #HepBV #Phases ... #Treatment #Management ... #diagnosis #hepatology