13 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Primary Thrombotic ... Differential Diagnosis Table ... • Thrombotic ... Thrombocytopenic Purpura ... Microangiopathy #TMA #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura ... Thrombocytopenic #Purpura ... #management #treatment ... #rheumatology # ... hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... testing for TTP #Thrombotic ... thrombocytopenic #purpura ... Comparison #Diagnosis #Table ... #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS ... of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
, Thrombosis, Emboli ... disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... #differential #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... DIC • Severe Liver ... causes #treatment #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(Petechial or purpuric ... rash) • Heart, ... thrombocytopenia • Liver ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Eosinophilia, asthma, chronic ... mucositis - Rash ... - Thrombosis ... • HBV HCV • ... differential #diagnosis #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management