13 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... Thrombocytopenic Purpura ... Toxin-Mediated HUS ... HUS (aHUS) ... Microangiopathy #TMA #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... thrombocytopenic #purpura ... HemolyticUremicSyndrome #HUS ... Comparison #Diagnosis #Table ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disease - DIC/TTP/HUS ... : • DIC, TTP/HUS ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
HUS), Serum creatinine ... HUS) Treatment ... #management #treatment ... #rheumatology # ... hematology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... HBV and thus periodic ... HAV immunity; Liver ... Algorithm #Diagnosis #Management ... #Treatment #Hepatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS ... and Acute Fatty Liver ... Hemolysis, Elevated Liver ... AFLP #obstetrics #hematology ... #diagnosis #table
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
disease: > 2 • NASH ... , Chronic viral ... injury: > 3 • Chronic ... #chemistry #diagnosis ... #differential #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... DIC • Severe Liver ... causes #treatment #management ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(Petechial or purpuric ... rash) • Heart, ... thrombocytopenia • Liver ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... disease • Liver ... Malignancies • Chronic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management