19 results
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Infections: - ... Viral: VZV, HSV, ... HIV, CMV, HTLV ... #diagnosis #neurology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... : HCV infection, ... HBV infection, ... HIV infection ... DDX: • ANCA (Antineutrophil
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... Clinical Presentation ... : The clinical ... syndrome of HAD ... dementia #AIDS #Neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... with pulmonary TB ... #differential #TB ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... Lesions of the spinal ... • Inflammatory disorders ... parainfluenza, Coxsackie, HIV ... Differential #Diagnosis #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Cauda Equina Syndrome ... epidural hematoma • infections ... cord infarct • HIV ... infection/abscess ... diagnosis #causes #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Focal inflammatory disorder ... Transverse Myelitis - Clinical ... simplex virus, HIV ... , Hep A/B/CMV, TB ... diagnosis #management #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
Syndromes Spinal ... result in permanent neurologic ... Infarction - Infection ... syphilis, and HIV ... differential #diagnosis #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Principles of HIV-Associated ... in HIV: • CNS ... #HIV #CNS #Infections ... InfectiousDiseases #Neurology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... , HIV) • Glucocorticoid