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Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
vs Arterial Thrombosis ... • Nephrotic Syndrome ... Arterial Embolism ... #hematology #differential ... #diagnosis #vascular
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Echocardiogram, Vascular ... thrombosis) Venous ... #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

 -
: Rheumatologic ... - MCC systemic ... state (eg APLA) ... - Vascular: embolic ... / thrombotic, vasospasm
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Syndrome (APLS) ... FOR TESTING: • Vascular ... clinical episodes of arterial ... #Syndrome #Hypercoagulable ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... disease (VWD) • Hypercoagulable ... - PNH - APLS ... #hematology #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... processes: • Systemic ... syndrome • Warfarin-induced ... #rheumatology # ... hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... Asia • HLA-B51 association ... Disease: Arterial ... , dural sinus thrombosis ... signs #symptoms #rheumatology