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diagnosis sle differential hematology management treatment algorithm associations autoantibodies cerebritis champs classification cns complement holistic hypercoagulable hypocomplementemia low mnemonic neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Demyelinating Syndrome ... vasculopathy, thrombosis ... #Lupus #Erythematosus ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... lupus erythematosus ... #Lupus #Erythematosus ... #Diagnosis #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
RA, Sjogren's), antiphospholipid ... syndrome, atheroembolic ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #differential #hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... Antibody Syndrome ... • Scleroderma (Systemic
Holistic Management of Systemic Lupus • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
Lupus • Lifestyle ... Infection/vaccination, Thrombosis ... (antiphospholipid ... #Lupus #Erythematosus ... management #treatment #rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... Hypercoagulable Workup ... excluded Testing: • Lupus ... #Antiphospholipid
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... ischemia - Skin: erythematous ... - Thrombosis ... lupus erythematosus ... differential #diagnosis #rheumatology
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