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patterns vasculitis anca antibody antineutrophil aortitis arthritis arthropathies arthropathy cardiology causes cryoglobulinemia cryoglobulins disorders igg4 joint laboratory management monoarthritis monoarticular
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Diseases: • Homogeneous ... connective tissue disease ... #Antibodies #ANA ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... lupus erythematosus ... • Rheumatic Diseases ... #diagnosis #differential
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
vasculitis (rare) • Rheumatic ... Diseases: IgG4- ... (IgG4-RD), Rheumatoid ... lupus erythematosus ... #Diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... connective tissue disease ... 90% • Anti-GBM disease ... #antibodies #diagnosis ... diseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... diseases (i.e. ... #Diagnosis #Rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis, Behcet disease ... lupus erythematosus ... , Rheumatoid arthritis ... Goodpasture's Disease ... testing: anti-ANCA
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... secondary) • Rheumatoid ... Lupus - with Systemic ... Lupus Erythematosus ... #Diagnosis #Algorithm
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... with auto-immune diseases ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... lupus erythematosus ... #Disease #Rheumatoid ... #diagnosis #testing
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... (antinuclear antibodies ... , rheumatoid factor ... IgG4 #Related #Disease
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