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diagnosis lupus sle antibodies disease anca antineutrophil arthritis cerebritis cns comparison druginduced laboratory monoclonal neurology oncology paraproteinemias patterns phenotypes related
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... lupus erythematosus ... #Antinuclear #Antibody ... antibodies #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... (ANA) - 95% - Initial ... Summary #diagnosis #rheumatology ... #management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... SLE), Sjogren's Syndrome ... #patterns #rheumatology ... #diagnosis #differential
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... (antinuclear antibodies ... #phenotypes #workup ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... the formation of autoantibodies ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... Pleural effusions • Acute ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
95% (IgG anti-chromatin ... of autoantibodies ... months to years) Systemic ... Lupus Erythematosus ... comparison #table #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... lupus erythematosus ... (SLE) - Antinuclear ... antibody (ANA) ... diagnosis #testing #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... anemia due to cold IgG ... Paraproteinemias #Hematology ... #Monoclonal #Differential
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
lupus erythematosus ... - IGG4 - Hepatic ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management ... #rheumatology #
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