Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic disease antibodies table autoimmune hematology leukemia lymphocytic cll diagnosis management

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16 results

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

their Disease Associations ... (TTG) - Celiac disease ... #diagnosis #table ... #rheumatology # ... antibodies

Chronic Lymphocytic Leukemia (CLL) - Summary
Overview:
• Most common leukemia in adults
• Disorder of

Leukemia (CLL) ... chemotherapy for low-risk disease ... 3) Monoclonal antibodies ... #hematology #hemeonc ... #diagnosis #management

Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
• Lymphocytes accumulate in large numbers

Diagnosis: • ... cells can indicate disease ... #Lymphocytic #Leukemia ... #diagnosis #workup ... #oncology #hematology

Autoantibodies in Rheumatology
• Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and

Rheumatology • ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... #Rheumatology # ... #table

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

multisystemic disease ... associated with other diseases ... demyelinating disease ... #Rheumatology # ... Diagnosis #Management

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Decade Skin Disease ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease ... #Rheumatology

Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell

• Chronic lung disease ... Granulomatous disease ... • Liver diseases ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone

• Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... #rheumatology # ... table #ANA

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