Haglund syndrome rheumatology workup ucl autoantibodies diseases systemic disease antibodies table autoimmune igg4 antibody antinuclear rheumatic sle phenotypes associations

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Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

their Disease Associations ... Anti-CCP, Rheumatoid ... (TTG) - Celiac disease ... diseases #diagnosis ... #table #rheumatology

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... or Anti-NucIear Antibody ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... #patterns #rheumatology

Autoantibodies in Rheumatology
• Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and

Lupus (SLE): ANA ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... diagnosis #associations ... #table

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... with disease activity ... with auto-immune diseases ... #autoantibodies ... #table #ANA

Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of

Rheumatology Workup ... Diseases • Septic ... exclude inflammatory disease ... connective-tissue disease ... #Disease #Rheumatoid

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... Decade Skin Disease ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease

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