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table anca antineutrophil antinuclear antinxp2 behcet cerebritis comparison dermatology dermatomyositis druginduced monoclonal neurology paraproteinemias signs sjogrens symptoms tafro thrombocytopenia
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • ... Lupus (SLE): ANA ... Ill • ANCA Vasculitis ... #Rheumatology # ... diagnosis #associations
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... connective tissue disease ... #antibodies #diagnosis ... #rheumatology # ... diseases
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... and CNS • Headache ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
of autoantibodies ... Lupus Erythematosus ... : Chronic disease ... #table #rheumatology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Asia • HLA-B51 association ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... disease, myelopathy ... Thyroid Disease: ... #Rheumatology # ... Diagnosis #Management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Antibodies targeting ... had more severe disease ... #diagnosis #management ... #rheumatology #
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
multicentric Castleman disease ... lupus erythematosus ... infection, rickettsial disease ... , Lyme disease, ... #management #rheumatology
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