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differential lupus erythematosus ana antibodies management vasculitis anca antineutrophil autoimmune behcet chronic classification cll comparison druginduced hematology laboratory leukemia lymphocytic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... context of other symptoms ... : Lupus (SLE), Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
in drug-induced SLE ... connective tissue disease ... 90% • Anti-GBM disease ... #rheumatology # ... diseases
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - Arthritis ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #autoantibodies ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... pain (20%) Renal disease ... #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Inflammatory eye disease ... #signs #symptoms ... #rheumatology # ... disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... exclude inflammatory disease ... connective-tissue disease ... #Rheumatic #Disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, Arthritis, myalgia ... months) and of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... diseases, such ... atherosclerotic disease ... most important diseases
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such ... disease, drug reactions ... most important diseases ... (GRANULOMATOUS DISEASE ... HBV Kawasaki Disease
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