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diagnosis antibodies differential table classification erythematosus patterns vasculitis antibody comparison cryoglobulins disease druginduced laboratory management rheumatic rheumatoid testing types vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... lupus erythematosus ... in drug-induced SLE ... cases • Sjögren syndrome ... #ANCA #Antineutrophil
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... • Scleroderma (Systemic ... : P-ANCA (perinuclear ... ), C-ANCA (cytoplasmic ... diagnosis #associations
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... Syndrome (SS), ... (SLE), Systemic ... #Antibodies #ANA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (ANA) ANA or Anti-NucIear ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #patterns #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Systemic lupus ... searched for when ANA ... #autoantibodies ... #Systemic #lupus ... #table #ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... syndrome) #Cryoglobulinemia ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... • Anti-Ro/SSA autoantibodies ... Diagnosis: • ANCA-associated ... #Systemic #Lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... : - ANA > ... of autoantibodies ... : - ANA > ... #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Others: • Lupus ... lupus erythematosus ... LFT • ESR • ANA ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (SLE) - Antinuclear ... antibody (ANA) ... ACE level, CXR, ANCA ... multiple myeloma) • ANA
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