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diagnosis ana antinuclear erythematosus sle associations autoimmune classification comparison druginduced management mimickers myopathy myositis signs vasculitides vasculitis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Lupus (SLE): ANA ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... #associations #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... : The ANA patterns ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis ... #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... SLE), Sjogren's Syndrome ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... SLE-Related Auto-Antibodies ... #Diagnosis #autoantibodies ... #signs #symptoms ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... Symptoms (Sx) in ... ) pattern: antibodies ... ) pattern: is usually ... #diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... SLE-SSc-AlM overlap syndromes ... #Systemic #lupus ... #table #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... : • Symptoms limited
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months) and of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... slow onset and pattern ... Mechanic's hands Autoantibodies ... • Conduction system ... #differential #
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