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diagnosis differential erythematosus ana antinuclear autoimmune classification comparison druginduced mimickers vasculitides vasculitis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... Peptide (CCP) • Myositis ... • Scleroderma (Systemic ... diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
overlap syndromes ... #Antinuclear #autoantibodies ... #Systemic #lupus ... erythematosus #diagnosis #rheumatology ... #table #ANA
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... anemia 4% - Myositis ... #Systemic #Lupus ... #signs #symptoms ... #differential #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... months) and of autoantibodies ... months to years) Systemic ... : Chronic disease ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... Diagnosis: • ANCA-associated ... : • Symptoms limited ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Shawl sign ... (also seen in association ... Mechanic's hands Autoantibodies ... • Conduction system ... #Myopathy #rheumatology
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