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ana differential erythematosus lupus patterns table aortitis arthritis associations laboratory management phenotypes sle testing treatment
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... with different rheumatic ... and Associated Rheumatic ... • Rheumatic Diseases ... #patterns #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... hepatitis Anti-CCP, Rheumatoid ... (TTG) - Celiac disease ... #rheumatology # ... antibodies
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
vasculitis (rare) • Rheumatic ... Diseases: IgG4- ... Related Disease ... (IgG4-RD), Rheumatoid ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Diseases: • Homogeneous ... connective tissue disease ... #Antibodies #ANA ... #patterns #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... (antinuclear antibodies ... , rheumatoid factor ... #Related #Disease ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... connective-tissue disease ... #Disease #Rheumatoid ... #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... #autoantibodies ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... vasculitis, rheumatoid ... diseases (i.e. ... ) • Kikuchi disease ... #Rheumatology
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