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hematology algorithm champs classification complement conditions cryoglobulinemia cryoglobulins dermatology effusion erythematosus extrarticular functional gap globulin hemoptysis hypocomplementemia infectiousdiseases joint low
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... Atypical HUS, autoimmune ... antiphospholipid syndrome ... #differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... Dermatosis: Schamberg Disease ... #Diagnosis #hematology
Causes of Primary and Functional Mitral Regurgitation (MR) Causes of primary mitral regurgitation - Rheumatic heart
Rheumatic heart disease ... , Barlow's disease ... disease: Collagen ... vascular disease ... #Diagnosis #Cardiology
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Non-Infectious: • Rheumatologic ... : EGPA, Horton Disease ... , Takayasu Disease ... #Diagnosis #Causes ... #cardiology
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... / Autoimmune: ANCA-Assoc ... vasculitis (GPA ... • Valvular (Mitral ... #causes
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... • Whipple's disease ... , Vasculitis (e.g ... #joint #pain #differential ... #diagnosis #rheumatology
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
arthritis • Systemic ... connective tissue disease ... spondyloarthropathies • Vasculitis ... Post-cardiac injury syndrome ... #Causes #Cardiology
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Borrelia (Lyme Disease ... /VASCULITIS - Behcet ... Disease - Systemic ... Vogt-Koyanagi-Harada disease ... #Diagnosis #Causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease ... • Castleman's disease
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... diseases: - 10% ... classification #rheumatology
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