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diagnosis clinical differential management rheumatology algorithm nephrology rhabdomyolysis treatment causes comparison microscopy myopathy neurology pathology pathophysiology signs symptoms video workup
RHABDOMYOLYSIS • Characterized by skeletal muscle breakdown & necrosis. • Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. • Defined based
Creatine kinase (CK ... ) hallmark of rhabdomyolysis ... Defined based on CK ... • Half-life of CK ... and cefdinir #CK
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
Creatine kinase (CK ... CK may increase ... creatine kinase (CK ... are the hallmark ... CK functions as
Here are the morphological hallmarks of Rhabdomyosarcoma. - Broken arrow sign - tad-pole rhabdomyoblasts
morphological hallmarks ... Rhabdomyosarcoma #Hallmarks
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
weakness • Elevated CK ... rash • Elevated CK ... Elevated ESR, Normal CK ... mildly elevated CK ... Myositis: elevated CK
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Normal CK ... Weakness, Incr CK ... therapy), Normal CK
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... ASYMPTOMATIC: Macro CK ... Kinase #Elevated #CK
Usmle step 2 ck Pulmonary diseases (High yield points) #usmle #algorithm
Usmle step 2 ck
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
: Proximal • CK ... : Proximal • CK ... : Proximal • CK ... and distal • CK
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myopathies #ESR #CK
Hallmark ECG features of Ventricular Tachycardia (VT) AV indicates atrioventricular; LAD, left axis deviation; LBBB, left bundle
Hallmark ECG features
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