10 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... hemolytic uremic syndrome ... , Hematology 2012 ... #Differential #Algorithm
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... HLH syndrome 5. ... #Workup #Differential ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... HLH syndrome 5 ... #Workup #Differential ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... , Vasculitides, ... Kawasaki, Nephrotic syndrome
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... infections/fevers • Thrombocytopenia ... • Peripheral Pancytopenia ... aplastic anemia Treatment ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... Workup: • Complete ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Neutropenia, anemia, thrombocytopenia ... microglobulin Treatment ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
standing for: - Thrombocytopenia ... ANCA-associated vasculitis ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology ... #Thrombocytopenia