10 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash ... Differential Diagnosis Algorithm ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Anemia • Toxic Damage ... Autoimmune • ITP • SLE ... #Causes #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash ... #table #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... 6) An annular rash ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... Differential Diagnosis Algorithm ... soles • Discoid Lupus ... Papulosquamous #SkinRash ... #causes
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... mucositis - Rash ... vasculitis, and SLE ... differential #diagnosis #rheumatology ... #classification
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... NPSLE rare, Malar rash ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... #DIL #rheumatology