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diagnosis hivaids infections lupus opportunistic prevention neurology differential druginduced erythematosus summary syndrome systemic algorithm antimicrobials bacterial behcets capsulatum cerebritis clinical
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... concentration: > 750ng/mL and ... #rheumatology # ... pharmacology #levels ... #lupus #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Management Summary ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... • Azathioprine and ... #management #pharmacology ... #rheumatology
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS Preventing Bacterial Enteric Illness: • Antimicrobial
IDSA Recommendations ... • In rare cases ... #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB) •
IDSA - Clinical ... Individualized Treatment ... Tuberculosis #MDRTB #management ... #regimens #pharmacology ... #dosing #idsa #
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... muscles: “myasthenic crises ... immunologic assay - MuSK ... Myasthenia Crises ... Gravis #diagnosis #management
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... We may ask why are ... some time, let’s see ... about secondary causes ... always a good idea
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