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Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Characteristics of Old and ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
Antihypertensive Dose ... Comparison. ... Dosing #Conversion #Pharmacology ... #Hypertension #Management ... #Table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
10 g QD (adjust dose ... Usual maintenance dose ... g QD; increase dose ... #medications #pharmacology ... #table #comparison
Renal Tubular Acidosis (RTA) Diagnosis and Management
 • Distal (type 1) RTA
 • Proximal (type 2)
Acidosis (RTA) Diagnosis ... and Management ... type 2) RTA • Hyperkalemic ... #Management #nephrology ... #table
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
since they are not able ... phosphate levels and ... restricted due to hypercalcemia ... Only* #CKD #Nephrology ... #Dosing #Pharmacology
Emergency Therapy of Hyperkalemia
Therapy - Dose and Route - Onset of Action - Duration of Effect
Emergency Therapy of Hyperkalemia ... Therapy - Dose ... Hemodialysis #Hyperkalemia ... #management #pharmacology ... #table #treatment
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
of Hyperkalemia ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison ... #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Lower risk of hypercalcemia ... edgarvlermamd - Nephrology ... Phosphate #Binders #Table ... #Comparison #Pharmacology ... #Nephrology
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
vasoactive drug pharmacology ... Vasoactive #Drugs #pharmacology ... #inopressors #diagnosis ... #management #comparison ... #table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... and Management ... Elimination (see Table ... and management ... #Diagnosis #Management