11 results
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
abstinent from short-acting ... margin of safety in pharmacology ... the sublingual tablet ... Pharmacokinetics #Comparison ... #Table #Pharmacology
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
some Cholinergic Agonists ... Edrophonium • Used for diagnosis ... blockers • Has short ... #Pharmacology # ... Table #Summary
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Seizures, Beta-Agonists ... testing • Seen in Short ... Bacteria ferment and ... #criticalcare #
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Pathophysiology: 2 hit ... : 33% • Treatment ... : No • Treatment ... Reactions #hematology #diagnosis ... #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... V1 receptor-agonist ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
to be in ADHF starts ... & Dry) is the treatment ... #table #foamed ... heartfailure #chf #criticalcare ... icu #clinical #pharmacology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
affects the knee hip ... > Stiffness is short-lived ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... #JointPain #Diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... dryness: muscarinic agonists
Kaposi Sarcoma Forms
Kaposi Sarcoma (KS) is an endothelial cell cancer with an inflammatory component, which has
disease rare and ... immunosuppressive regimen MSM ... without HIV infection ... Sarcoma #Forms #comparison ... #table #diagnosis
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... breakdown of glycogen stores ... In both SK and AK ... #diagnosis #differential ... #criticalcare #