13 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... HUGE treatment ... thrombocytopenic #purpura ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura ... (TTP) Diagnosis ... HUS) Treatment ... RTX • Short-term ... #rheumatology #hematology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Palpable Purpura ... on tuberculosis treatment ... Vasculitis #clinical #photo ... #dermatology #skin ... #rash #physicalexam
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Bethanechol • Used in treatment ... Edrophonium • Used for diagnosis ... short duration ... Cholinergic #Agonists #Pharmacology ... #Table #Summary
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
calculators - HAS-BLED ... validated for VTE treatment ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology ... #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... #Coagulation #diagnosis ... #causes #treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
, but without treatment ... the palms of the hands ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... whereas edoxaban has ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
with wife, bit by his ... +purpuric rash → ... the key to the diagnosis ... Canimorsus #Skin #Rash #dermatology ... #clinical #photo
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
to be in ADHF starts ... & Dry) is the treatment ... & Dry” is the treatment ... #table #foamed ... icu #clinical #pharmacology