11 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Features of a Sickle ... blood vessels leading ... Crises can be precipitated ... The underlying pathophysiology ... of capillaries leading
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Thrombocytosis: cells ... tourniquet while drawing ... 7) - principal cells ... #causes #potassium ... #high #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... smooth muscle cells ... gastrointestinal osmotic gradient ... Differential #Diagnosis #Algorithm ... #Pathophysiology
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... • Key Features ... progressive organ dysfunction ... complement • Classification
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... and increased B-cell ... tissue: Epithelioid cells ... failure Clinical Features
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
accumulates in cells ... essential for cell ... Glycosylation - AGE cause ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... risk death), T-cell ... COMMON CAUSES + ... CLINICAL FEATURES
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... monophasic Pathophysiology ... Alterations: - Sensory features ... Pleocytosis > 100 cells ... • Infectious causes