22 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... and Reduction in HbA1c ... • Hemolytic anemia ... Splenomegaly, Sickle Cell ... Elevation #Reduction #HbA1c
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic Algorithm ... and Causes Increased ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... Decreased WBCs ... - Decreased/NormaI ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Decreased Megakaryopoiesis ... • Aplastic Anemia ... ITP • SLE • CLL ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... combination of: Decreased ... Hypochromic RBCs Decreased ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Differential Diagnosis Algorithm ... Deficiency (Eg Causes ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Basic labs for decreased ... liver disease, decrease ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Differential Diagnosis Algorithm ... Myelofibrosis Stem cell ... Toxins • Aplastic Anemia ... #Causes #Hematology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Cause - Decreased ... - Gitelman SIGNS ... ⁻ increase may cause ... ⁻ decrease may cause
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... between classical CLL ... • Neutropenia, anemia ... • Polyclonal increase ... workup #oncology #hematology