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diagnosis differential algorithm clinical management hematology workup pocus causes hepatology ultrasound microscopy pathophysiology treatment blood nephrology anemia cardiology pulmonary syndrome
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 1. Old samples
alterations to measured RBC ... samples cause RBCs ... a falsely low RBC ... Schistocytes #Pyknocytes #Elliptocytes ... Keratocyte #Blister #HelmetCells
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
Elliptocyte - ... elliptocytosis, elliptocytes ... #Blood #Smear #Elliptocyte
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Red Blood Cell (RBC ... Bite cell, Elliptocyte ... cell, Other RBC ... Howell-Jolly bodies #RBC
Urine Microscopy and Casts - Image Atlas Key - Squamous Epithelial Casts - Transitional Epithelial Cells - Renal Tubular
- Monomorphic RBCs ... - Dysmorphic RBCs ... Granular Casts - WBC ... Cast - RBC Cast
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... sometimes) Macrocytic RBC ... Bite Cell RBC: G6PD ... Oxidative drugs Elliptocyte
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Myeloproliferative anemia • Elliptocytes ... coagulopathy (DIC) #RBC
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
/ Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Thalassemia • RBC ... Disorder • RBC
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
hypertension • Unusual RBC ... pyropoikilocytes, elliptocytes ... acanthocytes - Consider RBC
Urinalysis Interpretation (UA) Bacteria, Leukocyte esterase, WBC, Nitrite, RBC, Epithelial cells, pH #Diagnosis #Urinalysis #Interpretation #Analysis
Leukocyte esterase, WBC ... , Nitrite, RBC,
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 The differential diagnosis for an elevated MCHC (mean corpuscular hemoglobin concentration) includes: Conditions with Abnormal RBCs: •
with Abnormal RBCs ... : • Abnormal RBC ... Xerocytosis • RBC
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