9 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Count - Differential ... Diagnosis Algorithm ... → Refer to hematology ... Vasculitides, IBD, Celiac disease ... #hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Pancytopenia - Differential ... < 1800/uL, • platelet ... sequestration (splenomegaly ... MatthewHoMD #Pancytopenia ... #hematology #workup
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Hemolytic anemia - Splenomegaly ... fever • Drug reactions ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
without platelet ... myelofibrosis and splenomegaly ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... ITP, unexplained pancytopenia ... #Workup #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... Causes: • Liver disease ... • Transfusion reactions ... #classification ... #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
common following platelet ... progresses to pancytopenia ... Borrellia (Lyme disease ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Graft Versus Host Disease ... progresses to pancytopenia ... Borrellia (Lyme disease ... #Transfusions #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Low Hb and platelets ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology ... #management