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diagnosis rheumatology sle vasculitis antinuclear patterns activation aortitis criteria cryoglobulinemia cryoglobulins dermatology eularacr laboratory macrophage management mas mimickers monoclonal paraproteinemias
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... : Systemic lupus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... lupus erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... Juvenile Idiopathic Arthritis ... lupus erythematosus ... Arthritis, Sjögren ... Juvenile Idiopathic Arthritis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Arteritis (GCA) ... , Takayasu's arteritis ... , Cogan's Syndrome ... Arthritis (RA), ... Systemic lupus
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... : - ANA 95-100% ... Diagnosis and Lupus ... #Lupus #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , inflammatory arthritis ... arthritis, adult-onset ... Arthritis: • ... Symptoms limited to: Arthritis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Lupus Erythematosus ... Clinical Domains ... • Arthritis domain ... least 2 joints • Neurologic ... #Lupus #Erythematosus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... • Systemic lupus ... idiopathic arthritis ... lupus erythematosus ... Diagnosis #Management #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... rheumatic diseases ... lupus erythematosus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
arthritis - Gram ... lupus erythematosus ... of Inflammatory Arthritis ... arthritis (RA) ... #Disease #Rheumatoid
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
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